Looking for a reliable vertical mouse in 2025? You’re not alone. With so many models available today, it’s easy to get lost—especially when descriptions are vague or customer reviews are all over the place. That’s why we decided to sort things out. Not by claiming to know everything, but by analyzing what sells well, what real users say, and what’s worth your attention both on paper and in practice. Our goal isn’t to drown you in technical details, but to guide you toward the best possible choices—without wasting hours comparing on your own. In short, a practical and hopefully useful guide.
Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
Natural handshake position : The Logitech MX Vertical's natural handshake position helps reduce muscular activity by 10 percent compared to a standard computer mouse - without any loss in overall performance
Improved wrist posture : This wired and wireless bluetooth mouse features a distinct 57 Degree vertical angle that reduces the pressure on your wrist; it also ensures your thumb is positioned comfortably on the thumb rest
User tested. Ergonomist approved : 88% of ergonomics professionals would recommend MX Vertical (Survey, Ergo Expo and IAE Florence 2018 attendees)
Advanced Optical Tracking : The 4 000 DPI high-precision optical mouse sensor results in 4x less hand movement (compared to cordless mouse 1 000 DPI) and reduces fatigue. The cursor speed switch instantly adjusts DPI speed and accuracy with the touch of a button
Easy-Switch and Flow-enabled : Connect to up to three Windows PCs, Macs, laptops and switch between them at the tap of a button or by simply moving the cursor from one screen to another with Logitech FLOW (Requires Logitech Options software)
Lift yourself up: When the desk life gets you down, lift yourself up with Logitech Lift Vertical Ergonomic Mouse - a great fit for small to medium right hands
Raise your hand into comfort: Rest on Lift upright mouse throughout the day, with a softly textured grip and snug thumb rest for level-above cosiness
57 degrees of sooooothe: Lift’s vertical shape helps wrists feel like “ahhh” at work, and promotes a more natural posture in the forearm, for day-long comfort and productivity
Relax into focus: Settle into work with a cordless mouse featuring easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling
Ergo-certified: Lift wireless vertical mouse has been designed, developed, tested and approved according to criteria set out by leading ergonomists
How to choose a good vertical mouse?
On the surface, choosing a vertical mouse seems simple. But once you dig in, it gets more complicated. Between technical differences, unfamiliar brands, and unclear features, it’s better to ask the right questions:
Usage: Will you use it daily or only occasionally? That heavily influences the right model.
Budget: No need to go for the most expensive one right away. What matters is the value for money.
Key factors:
Durability, build quality, lifespan
Truly useful features (not just marketing buzz)
User reviews, especially after weeks or months
Availability of customer service in case of issues
We’ve cross-checked multiple sources: Amazon data, detailed reviews, search trends… and a bit of intuition too—because numbers don’t tell the whole story. This mix allows us to build our ranking, which we update regularly. The goal isn’t to just list names but to guide you toward what truly works.
Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
800 / 1200 / 1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
Enters power saving mode (power is cut off completely) after 8 minutes idle, press right or left button for it to wake. Product dimensions: 120*62.8*74.8 mm; product weight: 3.4 oz.
Package includes: 1 Anker Wireless Vertical Ergonomic Optical Mouse (2 AAA batteries not included), 1 2.4G USB receiver (in the bottom of the mouse), 1 instruction manual. 18-month hassle-free warranty.
Natural handshake position : The Logitech MX Vertical's natural handshake position helps reduce muscular activity by 10 percent compared to a standard computer mouse - without any loss in overall performance
Improved wrist posture : This wired and wireless bluetooth mouse features a distinct 57 Degree vertical angle that reduces the pressure on your wrist; it also ensures your thumb is positioned comfortably on the thumb rest
User tested. Ergonomist approved : 88% of ergonomics professionals would recommend MX Vertical (Survey, Ergo Expo and IAE Florence 2018 attendees)
Advanced Optical Tracking : The 4 000 DPI high-precision optical mouse sensor results in 4x less hand movement (compared to cordless mouse 1 000 DPI) and reduces fatigue. The cursor speed switch instantly adjusts DPI speed and accuracy with the touch of a button
Easy-Switch and Flow-enabled : Connect to up to three Windows PCs, Macs, laptops and switch between them at the tap of a button or by simply moving the cursor from one screen to another with Logitech FLOW (Requires Logitech Options software)
Lift yourself up: When the desk life gets you down, lift yourself up with Logitech Lift Vertical Ergonomic Mouse - a great fit for small to medium right hands
Raise your hand into comfort: Rest on Lift upright mouse throughout the day, with a softly textured grip and snug thumb rest for level-above cosiness
57 degrees of sooooothe: Lift’s vertical shape helps wrists feel like “ahhh” at work, and promotes a more natural posture in the forearm, for day-long comfort and productivity
Relax into focus: Settle into work with a cordless mouse featuring easy-to-reach customisable buttons, whisper-quiet clicks and a SmartWheel for smooth, seamless scrolling
Ergo-certified: Lift wireless vertical mouse has been designed, developed, tested and approved according to criteria set out by leading ergonomists
GOODBYE STRAIN – This ergonomic mouse is the vertical solution to strain and pain. Its ergonomic shape brings your arm and wrist into a natural 60° position to work effortlessly
FEEL BETTER – A lightweight design and shaped to fit all sizes of hands this mouse will feel like a relief. Its thumb rest and rubber coating further improve grip and comfort
ACCURATE CONTROL – Ergonomics don’t have to be boring; with this vertical mouse you can access a 1000/1600 DPI optical sensor and two thumb buttons for accurate and quick control
PLUG & PLAY – Connect the Verto wired mouse with the 1.5m USB cable and you can start working instantly. The blue LED light will illuminate your mouse
LIGHT UP YOUR DAY – The stylish - yet subtle - light on the left side of the mouse adds a bit of flair to your workday
Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain.
1000/1600 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
1.5m/4.9ft USB cable length, product dimensions: 120*62.8*74.8 mm; product weight: 5.3 oz.
Package includes: 1 Anker Vertical Ergonomic Optical Mouse (with 4.9 ft cable), 1 instruction manual. Includes 18 month warranty and lifetime technical support guarantee.
【Ergonomic design and enhanced comfort】The wireless ergonomic mouse features an extended wrist rest that hugs the palm of your hand and promotes a more natural and relaxed position for your forearm and wrist. This design helps minimize the risk of injury from repeated strain and reduce muscle tension in your arms to ensure comfort throughout the day
【Connect up to 3 devices】This ergonomic wireless mouse offers both BT 5.0 and 2.4G USB dual connection modes, allowing it to connect to three different devices simultaneously. Switching between devices is as easy as clicking the mode switch button. Compatible with Windows 8, Windows 10, Mac OS X 10.12 or higher and Android 4.3 or higher (No RGB lighting!!!)
【Rechargeable Battery】The vertical mouse is equipped with a built-in 500mAh Li-ion battery, which can be charged via the supplied Type-C cable(For charging purposes only). After 30-minute inactivity, the mouse automatically switches to sleep mode to save energy and can be woken up by simply moving. Besides, the low battery indicator reminds you to charge the wireless mouse when the red light flashes
【Adjustable DPI and Practical Features】Our bluetooth ergo mouse features convenient forward/backward buttons for easy web browsing. The 1000/1600/2400 DPI levels offer higher sensitivity than conventional optical mice and enable precise optical tracking. In addition, the whisper-quiet click of the mouse helps you to focus on the essentials. !!!NOTE: All buttons are not programmable and the forward and back buttons are not compatible with Mac OS systems
【Warm Note】ProtoArc EM11 NL vertical bluetooth mouse is recommended for medium small hands(Palm size: <17.5CM and 17.5CM-19CM, about the length of 3 bank cards), mouse size 13.8*6.9*6.8cm (5.43*2.72*2.68in). To get a more comfortable fit and a better user experience, we recommend measuring the size of your hand before buying
Ergonomic Design for Comfort: The vertical mouse provides an ergonomic mouse solution with a comfortable grip, reducing wrist strain and promoting better posture for long-term use. Ideal for ergonomic mouse wireless needs. Mouse Dimensions: L x W x H 11.6 x 7.2 x 7.5 cm /4.57 x 3.03 x 2.95 inches.
Easy Plug and Play : With 2.4G wireless technology, this wireless ergonomic mouse offers stable and fast connections, transmission up to 10 meters. one - to - one receiver configuration eliminates any concerns about interference.
4-Level DPI Adjustment: It supports four DPI settings of 800, 1200, 1600, and 2400 for free adjustment. From documents and spreadsheets to design drawing or simple gaming operations. One mouse can meet the needs of multiple scenarios! this vertical mouse wireless offers the flexibility you need with just a click.
Rechargeable with Battery Indicator: Stay powered up includes a clear battery indicator light, This helps you stay informed and avoid worries about low power.
Wide Compatibility & Worry free service: Compatible with Windows 11/10/8/7/XP/Vista and Mac OS X/Linux/Android/iOS(13+), as long as your devices with USB-A ports.offer a 45-day no-reason refund policy and a 12-month replacement service for quality issues, ensuring you a worry-free shopping experience.
[4800 High-precision wireless mouse] The wireless computer mouse has 5 adjustable DPI levels (800-1600 (default)-2400-3200-4800), You can adjust the DPI of the PC wireless mouse to meet your different needs. With 4800DPI, the mouse can achieve faster cursor movement and greater accuracy, making it an excellent option for gamers, designers, and multiple-screen workers
[Ergonomic design] The wireless mouse adopts a vertical design that conforms to ergonomics, with a 57° tilting angle that allows the wrist joint to be in a natural and relaxed state when holding the mouse. This not only helps reduce hand fatigue and discomfort caused by the long-term use of USB wireless mice but also enjoy a more comfortable and longer-lasting office experience
[Quieter click] The wireless silent mouse can reduce 95% of clicking noise interference during use while ensuring optimal performance. This means that you can feel every click, but almost cannot hear any sound, without worrying about disturbing people around you. It is especially suitable for places such as bedrooms and libraries that require a quiet environment
[Energy-efficient] The wireless vertical mouse is powered by 2 AAA batteries (not included),and with the latest automatic sleep mode: The computer wireless mouse will enters power saving mode after 8 minutes idle (power is cut off completely),press right or left button for it to wake. Plus, the LED low-battery reminder light ensures you can focus on your work without worrying about battery life(Recommend purchasing branded batteries to ensure battery life)
[6 Buttons & Wide Compatibility] With 6 buttons, this cordless mouse greatly improves your efficiency and meets all your functional needs. The side buttons make browsing the web a breeze by allowing you to easily turn pages. (Note: The side button is invalid in Mac OS) Moreover, the cordless mouse for laptop is compatible with a wide range of systems, including Windows XP/7/8/10/11 and Mac OS X10.4
[6400 High-precision Wired Mouse] The wired ergonomic mouse has 4 adjustable DPI levels (6400/3200/1600/1000). You can adjust the DPI of the wired mouse to meet your different needs. With 6400DPI, the PC mouse can achieve faster cursor movement and greater accuracy, making it an excellent option for gamers, designers, and multiple-screen workers
[Ergonomic Design] The wired vertical mouse adopts a vertical design that conforms to ergonomics, with a 57° tilting angle that allows the wrist joint to be in a natural and relaxed state when holding the mice. This not only helps reduce hand fatigue and discomfort caused by the long-term use of a wired mouse but also enjoy a more comfortable and longer-lasting office experience
[Quieter click] The wired silent mouse can reduce 95% of clicking noise interference during use while ensuring optimal performance. This means that you can feel every click, but almost cannot hear any sound, without worrying about disturbing people around you. It is especially suitable for places such as bedrooms and libraries that require a quiet environment
[6 Buttons & Wide Compatibility] With 6 buttons, this ergonomic mouse greatly improves your efficiency and meets all your functional needs. The side buttons make browsing the web a breeze by allowing you to easily turn pages. Wired Mouse for Laptop compatible with Windows 11, 10, 8, 7, Windows XP, Vista, 2000, Linux, and Mac OS or later (Note: Side buttons do not work on MAC OS systems)
[Plug and Play] The wired computer mouse utilizes a USB connection, providing a stable and accurate connection without the need for any driver installation. Additionally, the 1.5m (4.9 ft) USB cable length satisfies your requirement for mouse usage distance
【Rechargeable Wireless Mouse】The wireless ergonomic mouse has a built-in 600mAh lithium battery that can be easily recharged by the supplied Type-C cable. It lasts for 60 days of use and 90 days standby on a full charge. Additionally, the ergonomic mice enter power-saving mode (completely cutting off power) after being idle for about 8 minutes; you can wake it by pressing the right or left button. The ON/OFF switch and intelligent sleep mode also help to save energy. No need to charge the Rechargeable mouse frequently.
【Fast Switching Between Three Devices】The Bluetooth mice feature Bluetooth 5.0, 3.0 and USB-A receiver modes for connectivity. When connected via Bluetooth (Bluetooth mode supports simultaneous connections to two devices), the vertical mice effectively reduce need for a USB-A port, making it ideal for devices without USB ports. Simply press the button on the back to easily switch between the two modes.(Note: The 2.4GHz receiver is built into the bottom of the mouse).
【Right Handed Ergonomic Design】The Right handed wireless mouse features a vertical ergonomic design with a 52° tilt angle. It positions your palm near-vertically, unlike traditional mice; it keeps your wrist joint natural and relaxed, minimizing fatigue and discomfort from prolonged use. This design offers ultimate comfort, a more enjoyable and longer-lasting office experience. (Note: Mouse is designed for right-handed use only).
【Higher DPI & 6 Adjustable Levels】This vertical ergonomic mouse is equipped with a high-performance chip and features 6 adjustable DPI levels (4800/3200/2400/1600/1200/800) to meet your daily needs. When changing the DPI, the light will flash, with the number of flashes corresponding to the DPI level.
【Silent Mouse】The vertical mouse provides nearly silent clicks, helping avoid disturbances to others and ensuring your work or study remains undisturbed (Note: Only the left and right click buttons of the mouse are silent; other function buttons are not silent). The side buttons make browsing the web a breeze by allowing you to easily turn pages. (Note: The side buttons are not programmable, side buttons are invalid in macOS)
Frequently Asked Questions (FAQ)
What is the best vertical mouse? It depends on your needs, but the top 3 products are generally the most balanced options.
How do I maintain it properly? It varies by model. The best approach is to follow the manufacturer’s recommendations (yes, reading the manual is worth it).
Where to buy it with confidence? Amazon remains a solid choice: wide selection, easy returns, and tons of user reviews—hard to beat.
Do I need a big-name brand? Not necessarily. Lesser-known brands can be surprisingly good, with well-designed products that rival top names—at a lower cost. Don’t overlook them just because the name is unfamiliar.
What are the most common pitfalls? A super low price might be tempting but could signal major compromises (build quality, reliability, nonexistent support…). Also beware of product pages with no reviews or vague comments. Spend a few minutes reading real feedback—this is often where the most valuable info is.
How is our ranking built?
We don’t claim to have a magic formula. In reality, it’s a blend of data—ratings, sales volume, review frequency—and observation. We watch for recurring themes in reviews, compare search trends, and yes, sometimes rely on our gut feeling. A great product isn’t just numbers. Our ranking aims to balance all of that: data, common sense, and a lot of time spent checking.
We analyze scores, sales frequency, genuine reviews (not just stars), and current search trends. Each model is rated using a consistent set of criteria. While it’s not perfect, it helps us stay fair and consistent. And we update our lists often, because products evolve—and so do we.
Why trust Topelio?
Topelio is an independent website—we don’t sell these products and we’re not tied to any brand. What drives us is clarity and usefulness. We aim to produce practical, readable, honest content. Our rankings are based on public data, complemented by our own experience. No shady partnerships or biased recommendations—just a genuine effort to save you time, and maybe money too.
Thanks for taking the time to read this guide. Choosing a vertical mouse might seem trivial, but it’s often more complicated than expected. Too many options, unclear product pages, and marketing promises that don’t help… That’s why we aimed to create a simple but solid comparison. With practical info, useful tips, and most importantly—a ranking based on reality. Take time to compare, read more reviews if needed, and choose based on your own priorities. What works for someone else might not be ideal for you. If this guide helped you, feel free to explore our other articles. We always try to add real value—without wasting your time. See you soon on Topelio.
