Looking for a reliable psoriasis treatments in 2025? You’re not alone. With so many models available today, it’s easy to get lost—especially when descriptions are vague or customer reviews are all over the place. That’s why we decided to sort things out. Not by claiming to know everything, but by analyzing what sells well, what real users say, and what’s worth your attention both on paper and in practice. Our goal isn’t to drown you in technical details, but to guide you toward the best possible choices—without wasting hours comparing on your own. In short, a practical and hopefully useful guide.
NO.1 DOCTOR RECOMMENDED OINTMENT IN THE UK: Hydromol Ointment is the No.1 recommended ointment by doctors in the UK.
MANAGES ECZEMA, PSORIASIS AND OTHER DRY SKIN CONDITIONS: Our ointment is for the management of eczema, psoriasis and for other dry skin conditions, particularly as a night treatment
FORMS A PROTECTIVE SKIN BARRIER: Hydromol ointment helps to soothe, moisturise and protect the skin by forming a protective barrier on the surface of the skin to seal in moisture and prevent water loss
3 IN 1 OINTMENT: This 3 in 1 ointment can be used as a leave-on emollient, a moisturising bath additive and as an alternative to soap
FREE FROM: Hydromol Ointment is free from major skin irritants including preservatives, colours, fragrances and Sodium Lauryl Sulfate (SLS)
TREAT SYMPTOMS OF PSORIASIS – E45 Psoriasis Cream has been formulated to treat and prevent psoriasis and dermatitis symptoms and has been scientifically proven to reduce scaling itching, redness, roughness and hardening of the skin. The moisturising cream is full of nourishing ingredients that hydrate and stabilise the skin’s barrier, as well as supporting the skin’s natural regeneration process. It helps with dry, itchy, red, flaky skin and reduces roughness and hardening of psoriasis plaques.
WHAT IS PSORIASIS? – Psoriasis is a long-lasting skin condition which causes flaky patches of skin which form scales. These patches can appear anywhere on the body but most commonly the elbows, knees, scalp, and lower back. They can look pink or red and the scales white or silvery, and on darker skin the patches can look purple or dark brown with grey scales. The patches can be sore and itchy. E45 Psoriasis Cream is intended for the treatment and prevention of psoriasis and dermatitis symptoms.
REDUCE INFLAMMATION - E45 Psoriasis Cream contains Ectoin, a natural cell-protective molecule with inflammation-reducing and membrane-stabilising properties. Our Cream relieves and calms irritated and damaged skin by reducing inflammatory reactions and supporting the regeneration process of the skin. This cream is suitable for long term use and is a steroid-free psoriasis treatment. It should be gently massaged into the affected areas of skin 3 times a day or as often as needed.
QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
✅【FAST AND EFFECTIVE】This slows down the production of skin cells, relieves pain, reduces itching, moisturizes damaged areas of skin, repairs and restores skin elasticity, can strengthen the skin's natural barrier against irritants and natural harsh elements, making it easier to prevent skin problems relapse.
✅【SAFE】Organic herbal eczema treatment cream, using excellent natural plant formula, fragrance-free, skin-friendly, refreshing feeling makes you feel better. It can relieve skin itching, inhibit fungal infection, eczema, peeling, itchy feet, etc.
✅【HOW TO USE】This product is 100g. 1. Wash the skin before use; 2. Take an appropriate amount of moisturizing cream and apply it to the skin; 3. Keep using it to make the skin smoother and more tender.
✅【HELPS MOISTURIZE SKIN】Our skin moisturizer soothes and cares for the skin and is designed to help relieve dry, flaky skin. Make your skin smoother. Soothing and caring for the skin, our herbal formula is designed to help relieve itching associated with rashes, minor skin irritations, eczema and inflammation caused by psoriasis.
✅【USED AS AN EMOLLIENT】Relieves dry skin conditions prone to flare-ups such as eczema and psoriasis, soothes dry skin and dermatitis caused by frequent hand washing or use of alcohol-based hand sanitizers and gels, by forming effective dry barrier to moisturize and help repair skin.
How to choose a good psoriasis treatments?
On the surface, choosing a psoriasis treatments seems simple. But once you dig in, it gets more complicated. Between technical differences, unfamiliar brands, and unclear features, it’s better to ask the right questions:
Usage: Will you use it daily or only occasionally? That heavily influences the right model.
Budget: No need to go for the most expensive one right away. What matters is the value for money.
Key factors:
Durability, build quality, lifespan
Truly useful features (not just marketing buzz)
User reviews, especially after weeks or months
Availability of customer service in case of issues
We’ve cross-checked multiple sources: Amazon data, detailed reviews, search trends… and a bit of intuition too—because numbers don’t tell the whole story. This mix allows us to build our ranking, which we update regularly. The goal isn’t to just list names but to guide you toward what truly works.
NO.1 DOCTOR RECOMMENDED OINTMENT IN THE UK: Hydromol Ointment is the No.1 recommended ointment by doctors in the UK.
MANAGES ECZEMA, PSORIASIS AND OTHER DRY SKIN CONDITIONS: Our ointment is for the management of eczema, psoriasis and for other dry skin conditions, particularly as a night treatment
FORMS A PROTECTIVE SKIN BARRIER: Hydromol ointment helps to soothe, moisturise and protect the skin by forming a protective barrier on the surface of the skin to seal in moisture and prevent water loss
3 IN 1 OINTMENT: This 3 in 1 ointment can be used as a leave-on emollient, a moisturising bath additive and as an alternative to soap
FREE FROM: Hydromol Ointment is free from major skin irritants including preservatives, colours, fragrances and Sodium Lauryl Sulfate (SLS)
TREAT SYMPTOMS OF PSORIASIS – E45 Psoriasis Cream has been formulated to treat and prevent psoriasis and dermatitis symptoms and has been scientifically proven to reduce scaling itching, redness, roughness and hardening of the skin. The moisturising cream is full of nourishing ingredients that hydrate and stabilise the skin’s barrier, as well as supporting the skin’s natural regeneration process. It helps with dry, itchy, red, flaky skin and reduces roughness and hardening of psoriasis plaques.
WHAT IS PSORIASIS? – Psoriasis is a long-lasting skin condition which causes flaky patches of skin which form scales. These patches can appear anywhere on the body but most commonly the elbows, knees, scalp, and lower back. They can look pink or red and the scales white or silvery, and on darker skin the patches can look purple or dark brown with grey scales. The patches can be sore and itchy. E45 Psoriasis Cream is intended for the treatment and prevention of psoriasis and dermatitis symptoms.
REDUCE INFLAMMATION - E45 Psoriasis Cream contains Ectoin, a natural cell-protective molecule with inflammation-reducing and membrane-stabilising properties. Our Cream relieves and calms irritated and damaged skin by reducing inflammatory reactions and supporting the regeneration process of the skin. This cream is suitable for long term use and is a steroid-free psoriasis treatment. It should be gently massaged into the affected areas of skin 3 times a day or as often as needed.
QUALITY SKINCARE EVERY DAY – For 60 years, E45 has been a skincare expert in dry and itchy skin and treatment for eczema, psoriasis, ichthyosis and other dry skin conditions. We understand the importance of quality everyday products that care for your skin with minimal fuss. The E45 range of products has been developed for different skin types and parts of the body and works hard to protect and maintain skin health. It has proven dermatological expertise dedicated to vulnerable dry skin.
HISTORY OF E45 – We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin. In 1963 physicians noticed the benefits of E45 cream for dry skin conditions and our cream was introduced to pharmacy and retail in 1980. We’ve continued to create products with patients and their skin in mind. We strive to continue to serve the needs of patients and healthcare professionals and produce better treatment options for patients' skincare routines.
✅【FAST AND EFFECTIVE】This slows down the production of skin cells, relieves pain, reduces itching, moisturizes damaged areas of skin, repairs and restores skin elasticity, can strengthen the skin's natural barrier against irritants and natural harsh elements, making it easier to prevent skin problems relapse.
✅【SAFE】Organic herbal eczema treatment cream, using excellent natural plant formula, fragrance-free, skin-friendly, refreshing feeling makes you feel better. It can relieve skin itching, inhibit fungal infection, eczema, peeling, itchy feet, etc.
✅【HOW TO USE】This product is 100g. 1. Wash the skin before use; 2. Take an appropriate amount of moisturizing cream and apply it to the skin; 3. Keep using it to make the skin smoother and more tender.
✅【HELPS MOISTURIZE SKIN】Our skin moisturizer soothes and cares for the skin and is designed to help relieve dry, flaky skin. Make your skin smoother. Soothing and caring for the skin, our herbal formula is designed to help relieve itching associated with rashes, minor skin irritations, eczema and inflammation caused by psoriasis.
✅【USED AS AN EMOLLIENT】Relieves dry skin conditions prone to flare-ups such as eczema and psoriasis, soothes dry skin and dermatitis caused by frequent hand washing or use of alcohol-based hand sanitizers and gels, by forming effective dry barrier to moisturize and help repair skin.
Reduces Redness and Scaling: Specially formulated to target the core symptoms of psoriasis, our cream helps diminish the appearance of red patches and silvery scales. Regular application can lead to a smoother skin texture and a more even skin tone, visibly reducing the signs of irritation.
Deeply Moisturizes: Infused with high-quality Sunflower Seed Oil known for its hydrating properties, the cream penetrates deep into the skin to provide lasting moisture. Helps to restore the skin's natural barrier, preventing further moisture loss and maintaining skin elasticity.
Soothes Itching and Discomfort: Contains naturally derived ingredients that are known to soothe and calm irritated skin, providing relief from the persistent itchiness that can accompany psoriasis. The anti-inflammatory properties of essential oils like Tea Tree and Thyme contribute to reducing discomfort upon application.
Enriched with Natural Oils: Boasts a blend of natural oils and emollients that nourish the skin, promoting healing and regeneration. Tea Tree Oil provides antibacterial benefits, while Thyme Essential Oil is known for its antiseptic properties, contributing to the overall health of your skin.
Free from Harsh Chemicals: Our Psoriasis Relief Cream is free from harsh chemicals like parabens, sulfates, and phthalates, making it suitable for long-term use and for those with sensitive skin.
FROM DOUBLEBASE: Dry Skin Emollient is part of the widely prescribed ‘Doublebase’ brand for problem skin conditions including eczema, psoriasis and dermatitis
CLINICALLY PROVEN*: Doublebase Dry Skin is a clinically proven, high-performance emollient that provides prolonged protection against dryness. Dryness can be a leading cause of discomfort in problem skin conditions such as eczema, psoriasis and dermatitis
PRESCRIPTION HERITAGE: Doublebase Dry Skin is from the makers of the most prescribed emollient gel brand. Doublebase is for treating problem dry skin conditions including eczema, psoriasis and dermatitis
UNIQUE FORMULATION FOR EFFECTIVE DRY SKIN RELIEF: The Dry Skin formula combines the high emollient content of a cream with the easy absorption of a gel. Dry Skin’s innovative gel formulation breaks down on contact with the natural salts in the skin, allowing it to be easily absorbed into the stratum corneum (top layer of the skin)
LONG-LASTING HYDRATION: Dry Skin is a long-lasting, high-performance emollient that provides a lasting, protective barrier of oils, even after gentle washing
Treats and relieves psoriasis symptoms: Designed to treat itching, scaling and thickened skin
Unique formulation: Normalises skin cell production and maturation time – Activates the skin’s own repair mechanism to strengthen and restore the skin’s barrier
Creates a protective layer on top of the skin: Does not dry out your skin, absorbs easily and is non-greasy
Dermatologically tested: Contains no steroids, tar, Vitamin D3 analogues, Vitamin A derivatives, or sulphur
Suitable for adults and children from fourteen years of age
Targeted Relief for Scalp & Skin Flaking Dryness: Steriod free cream helps soften buildup, reduce visible flakes, and refresh dry, uneven skin on both the scalp and body.
Botanical Formula Inspired by Herbal Wisdom: Infused with15 traditional plant extracts, including Sophora Root, Dictamni Cortex, and Stemona, known for their calming and purifying properties.
Gentle Hydration for Irritated or Sensitive Areas: Infused with glycerin and sodium hyaluronate to moisturize and support a healthy skin barrier—ideal for dry, tight, or uncomfortable patches.
Soothing Care Without Harsh Chemicals: Free from steroids, parabens, and artificial fragrance. Suitable for sensitive skin types seeking a natural-based care routine.
For Scalp, Hairline, Ears, and Body Folds: Designed for multi-area use—perfect for dry or oily-prone zones like the scalp, back of the ears, neck folds, and more.
Calms Irritated, Dry Skin - Keep skin redness and itchiness at bay. Our psoriasis, folliculitus and eczema capsules contain skin-loving nutrients and botanicals that may provide natural itch relief, combat redness, and reduce skin swelling with each dose.
Targets Cause of Irritation - This vegan multivitamin works as a body moisturiser from within. Its vitamins and amino acids target the cause, not the symptoms of skin discomfort by blocking attacks on healthy skin cells.
All-Natural Nourishment - Experience better skin health with 31 powerful ingredients from nature! Our immune system vitamins improve the quality of your skin and hair with botanicals and antioxidants. They do not contain additives, preservatives, or colouring, so you get a pure dose of wellness.
Easy to Swallow - This fast-absorbing itchy skin relief is easy to take and digest. Don’t like swallowing pills? Simply open the vegan shell and sprinkle the powder into smoothies, juices, yoghurts, and more.
Quality You Can Trust - As part of our dedication to honesty and transparency, these immune support supplements are manufactured under strict conditions. Our ISO 22000:2018 registration, a significant step illustrating our values, goals and promises, is further proof of our commitment.
EFFECTIVE RELIEF FROM PSORIASIS SYMPTOMS: Our Psoriasis Relief Serum is specifically formulated to act as an effective psoriasis treatment, reducing symptoms like irritation, itching, and discomfort. It works swiftly to calm inflamed skin for improved skin health.
NATURAL BLEND OF INGREDIENTS: With a potent mix of castor oil, salicylic acid, tea tree oil, and lemongrass oil, our serum offers a natural solution for scalp psoriasis treatment and itchy scalp treatment. These ingredients work synergistically to nourish and soothe the skin.
SOFTENS AND LOOSENS SCALES AND PLAQUES: Regular use of our Psoriasis Relief Serum not only acts as a psoriasis scalp treatment but also softens and loosens scales and plaques, improving the appearance and comfort of affected areas.
EASY APPLICATION AND QUICK ABSORBTION: Designed for quick absorption, this non-greasy salicylic acid hair scalp treatment seamlessly fits into your daily skincare routine without leaving any residue.
FREE FROM HARSH CHEMICALS, PARABENS AND ARTIFICIAL FRANGRANCES: Our scalp oil for dry itchy scalp is formulated without unnecessary additives, making it gentle and safe for individuals with sensitive skin.
【Ultra Relief Power】Our Eczema & Psoriasis Cream can help relieve the itching, dry, cracked Irritated skin, scaling and pain associated with Psoriasis, eczema, Seborrheic dermatitis, and Folliculitis
【Non-Greasy Material】 Mild Herbage Extraction, The non-greasy material is the perfect solution to moisturize your skin! It's a lightweight formula that absorbs quickly, providing relief from dryness and itchiness, heal the skin from within
【Control Reoccurrence】Our advanced formula is specially formulated to provide relief from the symptoms of psoriasis and eczema. The natural ingredients help control the recurrence of psoriasis symptoms
【Free Of Harsh Chemicals】Nupharmisto eczema lotion is free of harsh and toxic chemicals that can irritate sensitive skin. We use only the highest quality ingredients that are safe for all skin types. Our Psoriasis lotion is completely natural with no additives or preservatives
【Satisfaction or 100% Refund】We're confident that you'll be satisfied with your purchase. If for some reason, the psoriasis cream doesn't meet your needs - just reach out and we will refund 100% of what was paid!
Frequently Asked Questions (FAQ)
What is the best psoriasis treatments? It depends on your needs, but the top 3 products are generally the most balanced options.
How do I maintain it properly? It varies by model. The best approach is to follow the manufacturer’s recommendations (yes, reading the manual is worth it).
Where to buy it with confidence? Amazon remains a solid choice: wide selection, easy returns, and tons of user reviews—hard to beat.
Do I need a big-name brand? Not necessarily. Lesser-known brands can be surprisingly good, with well-designed products that rival top names—at a lower cost. Don’t overlook them just because the name is unfamiliar.
What are the most common pitfalls? A super low price might be tempting but could signal major compromises (build quality, reliability, nonexistent support…). Also beware of product pages with no reviews or vague comments. Spend a few minutes reading real feedback—this is often where the most valuable info is.
How is our ranking built?
We don’t claim to have a magic formula. In reality, it’s a blend of data—ratings, sales volume, review frequency—and observation. We watch for recurring themes in reviews, compare search trends, and yes, sometimes rely on our gut feeling. A great product isn’t just numbers. Our ranking aims to balance all of that: data, common sense, and a lot of time spent checking.
We analyze scores, sales frequency, genuine reviews (not just stars), and current search trends. Each model is rated using a consistent set of criteria. While it’s not perfect, it helps us stay fair and consistent. And we update our lists often, because products evolve—and so do we.
Why trust Topelio?
Topelio is an independent website—we don’t sell these products and we’re not tied to any brand. What drives us is clarity and usefulness. We aim to produce practical, readable, honest content. Our rankings are based on public data, complemented by our own experience. No shady partnerships or biased recommendations—just a genuine effort to save you time, and maybe money too.
Thanks for taking the time to read this guide. Choosing a psoriasis treatments might seem trivial, but it’s often more complicated than expected. Too many options, unclear product pages, and marketing promises that don’t help… That’s why we aimed to create a simple but solid comparison. With practical info, useful tips, and most importantly—a ranking based on reality. Take time to compare, read more reviews if needed, and choose based on your own priorities. What works for someone else might not be ideal for you. If this guide helped you, feel free to explore our other articles. We always try to add real value—without wasting your time. See you soon on Topelio.
